NanoBizExchange.com » Nanoparticles

Cytotoxicity and cellular uptake evaluation of mitoxantrone-loaded poly(lactic acid-co-lysine) arginine-glycine-aspartic acid nanoparticles

NanoBizExchange.com — Tue, 18 Jan 2011 20:52:51 +0000

This study was undertaken to evaluate the in vitro characteristics of poly(lactic acid-co-lysine) arginine-glycine-aspartic acid (PLA-PLL-RGD) nanoparticles (NPs) loaded with mitoxantrone; the association processes of NPs with MCF-7 cells, including binding and effective internalization, were investigated in vitro.
Journal of Applied Polymer Science, 119(2): 1011-1015 (January 2011)
International Council on Nanotechnology, Rice University – Virtual Journal

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Mineralization of Monodispersed CdS Nanoparticles on Polyelectrolyte Superstructure Forming an Electroluminescent “Necklace-of-Beads”

NanoBizExchange.com — Tue, 18 Jan 2011 20:52:48 +0000

We report a nonmicellar method to synthesize monodisperse semiconducting nanoparticles templated on polymer chains dissolved in solution at high yield. The monodispersity is achieved due to the beaded necklace morphology of the polyelectrolyte chains in solution where the beads are nanometer-scale nodules in the polymer chain. The resultant structure is a nanoparticles studded necklace where the particles are imbedded in the beads. Multiple cycles of synthesis on the polymer template yield nanoparticles of identical size, resulting in a nanocomposite with high particle fraction. The resultant nanocomposite has beaded-fibrilar morphology with imbedded nanoparticles and can be solution-casted to make electroluminescent thin film device.
Papers in Nanotechnology

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Self-Assembling Gold Nanoparticles Use Light to Kill Tumor Cells

NanoBizExchange.com — Tue, 29 Jun 2010 14:16:12 +0000

When irradiated with light, gold nanoparticles become hot quickly, hot enough to generate explosive microbubbles that will kill nearby cancer cells, a physical process known as the photothermal effect. To boost this approach, researchers at the University of California, Los Angeles, have developed a method for creating supramolecular assemblies of gold nanoparticles that function as highly efficient photothermal agents of a size designed to optimize their delivery to tumors. Hsien-Rong Tseng, a member of the Nanosystems Biology Cancer Center, and his colleagues reported their work in the journal Angewandte Chemie International Edition.
NCI Alliance for Nanotechnology in Cancer – Nanotech News

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Self-Assembly of Nanoparticles on Live Bacterium: An Avenue to Fabricate Electronic Devices

NanoBizExchange.com — Tue, 29 Jun 2010 14:10:59 +0000

Recently, hybrid structures of microorganisms with inorganic nanoscale moieties have received great interest owing to their potential in fabricating electronic systems. The electronic properties of metal nanoparticles, as a result of the singleelectron transport of current,[1] make them ideal materials for nanodevices. Concomitantly, the nanostructure of microorganisms such as bacteria,[2] viruses,[3, 4] and yeast[5] are attractive scaffolds for the templating of metal nanoparticles through the interactions of the former with surface charges and the affinity of certain metals for specific biological molecules.[2-7] However, the key challenges in building hybrid devices are 1) to pattern nanostructures without destroying the biological construct of the microorganism and 2) to achieve active integration of a biological response to the electrical transport in a nanoparticle device.
Papers in Nanotechnology

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Optimized Method for Preparation of TiO2 Nanoparticles Dispersion for Biological Study

NanoBizExchange.com — Tue, 29 Jun 2010 14:10:56 +0000

The objective of this study was to develop a practical method to prepare a stable dispersion of TiO2 nanoparticles for biological studies. TiO2 (rutile/anatase) dispersions were prepared in distilled water following by treated with different ultrasound energies and various dispersion stabilizers.
Journal of Nanoscience and Nanotechnology, 10(8): 5213-5219 (August 2010)
International Council on Nanotechnology, Rice University – Virtual Journal

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